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VASOPRESSIN


DIR Classification


Classification:Moderate-DIR concern
Severity Score:2

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • OVERDOSAGE
  • Overdosage with Vasostrict® can be expected to manifest as consequences of vasoconstriction of various vascular beds (peripheral, mesenteric, and coronary) and as hyponatremia. In addition, overdosage may lead less commonly to ventricular tachyarrhythmias (including Torsade de Pointes), rhabdomyolysis, and non-specific gastrointestinal symptoms.
  • Direct effects will resolve within minutes of withdrawal of treatment.

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
Rhabdomyolysis
0
42912
Other ADRs
119
14117160

Odds Ratio = N/A

Drug Property Information



ATC Code(s):
  • H01BA06 - vasopressin
    • H01BA - Vasopressin and analogues
    • H01B - POSTERIOR PITUITARY LOBE HORMONES
    • H01 - PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
    • H - "SYSTEMIC HORMONAL PREPARATIONS, EXCL. "
  • H01BA01 - vasopressin
    • H01BA - Vasopressin and analogues
    • H01B - POSTERIOR PITUITARY LOBE HORMONES
    • H01 - PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
    • H - "SYSTEMIC HORMONAL PREPARATIONS, EXCL. "
Active Ingredient:vasopressin, unspecified
Active Ingredient UNII:Y87Y826H08
Drugbank ID:DB00067
PubChem Compound:N/A
CAS Number:11000-17-2
Dosage Form(s):injection
Route(s) Of Administrator:intravenous
Daily Dose:
  • 4U H01BA01
Chemical Structure:
SMILE Code:
-

Reference

COHORT STUDY:

N/A

OTHER REFERENCE(S):

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[Sitprija Visith]
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[Pitts T O,Van Thiel D H]
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[Affarah H B,Mars R L,Someren A,Smith H W,Heymsfield S B]
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