Search for drugs:
Typing the drug name to query
PROTRIPTYLINE HYDROCHLORIDE
DIR Classification
Classification:Moderate-DIQT concern
Severity Score:3.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- CONTRAINDICATIONS
- Protriptyline is contraindicated in patients taking cisapride because of the possibility of adverse cardiac interactions including prolongation of the QT interval, cardiac arrhythmias and conduction system disturbances.
- This drug should not be used during the acute recovery phase following myocardial infarction.
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
0
24092
Other ADRs
52
38381535
Odds Ratio = 0.0
Drug Property Information
ATC Code(s):
- N06AA11 - protriptyline hydrochloride
- N06AA - Non-selective monoamine reuptake inhibitors
- N06A - ANTIDEPRESSANTS
- N06 - PSYCHOANALEPTICS
- N - NERVOUS SYSTEM
Active Ingredient:PROTRIPTYLINE HYDROCHLORIDE
Active Ingredient UNII:44665V00O8
Drugbank ID:DB00344
PubChem Compound:4976
CTD ID:D011530
PharmGKB:PA451168
CAS Number:438-60-8
Dosage Form(s):tablet, film coated
Route(s) Of Administrator:oral
Daily Dose:
- 30.0 mg/day N06AA11
Chemical Structure: 
SMILE Code:
CNCCCC1C2=CC=CC=C2C=CC2=CC=CC=C12
CNCCCC1C2=CC=CC=C2C=CC2=CC=CC=C12
Reference
N/A
Disclaimer:
The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.
Any mention of commercial products is for clarification and not intended as endorsement.