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IOPAMIDOL


DIR Classification


Classification:Ambiguous
Severity Score:1.0

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • ADVERSE REACTIONS
  • Following coronary and ventricular injections, certain electrocardiographic changes (increased QTc, increased R-R, T-wave amplitude) and certain hemodynamic changes (decreased systolic pressure) occurred less frequently with ISOVUE (lopamidol Injection) than with diatrizoate meglumine and diatrizoate sodium injection; increased LVEDP occurred less frequently after ventricular iopamidol injections.

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
QT Prolongation
1
24091
Other ADRs
3984
38377603

Odds Ratio = 0.4

Drug Property Information



ATC Code(s):
  • V08AB04 - iopamidol
    • V08AB - "Watersoluble, nephrotropic, low osmolar X-ray contrast media"
    • V08A - "X-RAY CONTRAST MEDIA, IODINATED"
    • V08 - CONTRAST MEDIA
    • V - VARIOUS
Active Ingredient:IOPAMIDOL
Active Ingredient UNII:JR13W81H44
Drugbank ID:DB08947
PubChem Compound:65492
CTD ID:D007479
PharmGKB:
CAS Number:60166-93-0
Dosage Form(s):injection, solution
Route(s) Of Administrator:intravascular
Daily Dose:
Chemical Structure:
SMILE Code:
C[C@H](O)C(=O)NC1=C(I)C(C(=O)NC(CO)CO)=C(I)C(C(=O)NC(CO)CO)=C1I

Reference

N/A

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