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SELEXIPAG


DIR Classification


Classification:Ambiguous
Severity Score:1.0

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • CLINICAL PHARMACOLOGY
  • Pharmacodynamics
  • Cardiac electrophysiology
  • At the maximum tolerated dose of 1600 mcg twice daily, selexipag does not prolong the QT interval to any clinically relevant extent.

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
QT Prolongation
4
24088
Other ADRs
50204
38331383

Odds Ratio = 0.127

Drug Property Information



ATC Code(s):
  • B01AC27 - selexipag
    • B01AC - Platelet aggregation inhibitors excl. heparin
    • B01A - ANTITHROMBOTIC AGENTS
    • B01 - ANTITHROMBOTIC AGENTS
    • B - BLOOD AND BLOOD FORMING ORGANS
Active Ingredient:SELEXIPAG
Active Ingredient UNII:5EXC0E384L
Drugbank ID:DB11362
PubChem Compound:9913767
CTD ID:C523468
PharmGKB:
CAS Number:475086-01-2
Dosage Form(s):kit; tablet, coated
Route(s) Of Administrator:oral
Daily Dose:
  • 1.8 mg/day B01AC27
Chemical Structure:
SMILE Code:
CC(C)N(CCCCOCC(=O)NS(C)(=O)=O)C1=NC(C2=CC=CC=C2)=C(N=C1)C1=CC=CC=C1

Reference

N/A

Disclaimer:

The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.

Any mention of commercial products is for clarification and not intended as endorsement.