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RADIUM RA 223 DICHLORIDE
DIR Classification
Classification:Ambiguous
Severity Score:1.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- CLINICAL PHARMACOLOGY
- Cardiac Electrophysiology
- The effect of a single dose of 55 kBq/kg of radium-223 dichloride on the QTc interval was evaluated in a subgroup of 29 patients (21 received Xofigo and 8 received placebo) in the randomized clinical trial. No large changes in the mean QTc interval (i.e., greater than 20 ms) were detected up to 6 hours post-dose. The potential for delayed effects on the QT interval after 6 hours was not evaluated.
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
0
24092
Other ADRs
120
38381467
Odds Ratio = 0.0
Drug Property Information
ATC Code(s):
- V10XX03 - radium ra 223 dichloride
- V10XX0 -
- V10XX - Various therapeutic radiopharmaceuticals
- V10X - OTHER THERAPEUTIC RADIOPHARMACEUTICALS
- V10 - THERAPEUTIC RADIOPHARMACEUTICALS
- V - VARIOUS
Active Ingredient:RADIUM RA-223 DICHLORIDE
Active Ingredient UNII:RJ00KV3VTG
Drugbank ID:DB08913
PubChem Compound:N/ADIR Classification
CTD ID:C581106
CAS Number:444811-40-9
Dosage Form(s):injection
Route(s) Of Administrator:intravenous
Daily Dose:
Chemical Structure: 
SMILE Code:
[Cl-].[Cl-].[223Ra++]
[Cl-].[Cl-].[223Ra++]
Reference
N/A
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