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DEXLANSOPRAZOLE


DIR Classification


Classification:Ambiguous
Severity Score:1.0

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • CLINICAL PHARMACOLOGY
  • Pharmacodynamics
  • Cardiac Electrophysiology
  • At a dose five times the maximum recommended dose, dexlansoprazole does not prolong the QT interval to any clinically relevant extent.

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
QT Prolongation
2
24090
Other ADRs
12084
38369503

Odds Ratio = 0.264

Drug Property Information



ATC Code(s):
  • A02BC06 - dexlansoprazole
    • A02BC - Proton pump inhibitors
    • A02B - DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    • A02 - DRUGS FOR ACID RELATED DISORDERS
    • A - ALIMENTARY TRACT AND METABOLISM
Active Ingredient:dexlansoprazole
Active Ingredient UNII:UYE4T5I70X
Drugbank ID:DB05351
PubChem Compound:9578005
CTD ID:D064748
PharmGKB:PA166110257
CAS Number:138530-94-6
Dosage Form(s):capsule, delayed release
Route(s) Of Administrator:oral
Daily Dose:
  • 30.0 mg/day A02BC06
Chemical Structure:
SMILE Code:
CC1=C(OCC(F)(F)F)C=CN=C1C[S@@](=O)C1=NC2=CC=CC=C2N1

Reference

N/A

Disclaimer:

The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.

Any mention of commercial products is for clarification and not intended as endorsement.