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ELUXADOLINE
DIR Classification
Classification:Ambiguous
Severity Score:1.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- CLINICAL PHARMACOLOGY
- Pharmacodynamics
- Cardiac Electrophysiology
- At a dose 10 times the maximum recommended dose (100 mg), VIBERZI does not prolong the QT interval to any clinically relevant extent.
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
2
24090
Other ADRs
5281
38376306
Odds Ratio = 0.604
Drug Property Information
ATC Code(s):
- A07DA06 - eluxadoline
- A07DA0 -
- A07DA - Antipropulsives
- A07D - ANTIPROPULSIVES
- A07 - "ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE "
- A - ALIMENTARY TRACT AND METABOLISM
Active Ingredient:ELUXADOLINE
Active Ingredient UNII:45TPJ4MBQ1
Drugbank ID:DB09272
PubChem Compound:11250029
CTD ID: C583636
CAS Number:864821-90-9
Dosage Form(s):tablet, film coated
Route(s) Of Administrator:oral
Daily Dose:
- 200.0 mg/day A07DA06
Chemical Structure: 
SMILE Code:
COC1=CC=C(CN([C@@H](C)C2=NC(=CN2)C2=CC=CC=C2)C(=O)[C@@H](N)CC2=C(C)C=C(C=C2C)C(N)=O)C=C1C(O)=O
COC1=CC=C(CN([C@@H](C)C2=NC(=CN2)C2=CC=CC=C2)C(=O)[C@@H](N)CC2=C(C)C=C(C=C2C)C(N)=O)C=C1C(O)=O
Reference
N/A
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The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.
Any mention of commercial products is for clarification and not intended as endorsement.