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POTASSIUM CHLORIDE
DIR Classification
Classification:Moderate-DIQT concern
Severity Score:2.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- OVERDOSAGE
- Symptoms
- The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, potentially fatal hyperkalemia can result.
- Hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5- 8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-waves, depression of S-T segment, and prolongation of the QT-interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L).
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
5
24087
Other ADRs
5760
38375827
Odds Ratio = 1.384
Drug Property Information
ATC Code(s):
- A12BA01 - potassium chloride
- A12BA - Potassium
- A12B - POTASSIUM
- A12 - MINERAL SUPPLEMENTS
- A - ALIMENTARY TRACT AND METABOLISM
Active Ingredient:POTASSIUM CHLORIDE
Active Ingredient UNII:660YQ98I10
Drugbank ID:DB00761
PubChem Compound:4873
CTD ID:D011189
PharmGKB:PA451055
CAS Number:7447-40-7
Dosage Form(s):capsule, extended release
Route(s) Of Administrator:oral
Daily Dose:
- 3.0 mg/day A12BA01
Chemical Structure: 
SMILE Code:
[Cl-].[K+]
[Cl-].[K+]
Reference
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