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SUMATRIPTAN SUCCINATE


DIR Classification


Classification:Ambiguous
Severity Score:1.0

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • ADVERSE REACTIONS
  • Cardiovascular
  • Abdominal aortic aneurysm, abnormal pulse, flushing, phlebitis, Raynaud syndrome, and various transient ECG changes (nonspecific ST or T wave changes, prolongation of PR or QTc intervals, sinus arrhythmia, nonsustained ventricular premature beats, isolated junctional ectopic beats, atrial ectopic beats, delayed activation of the right ventricle).

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
QT Prolongation
9
24083
Other ADRs
50067
38331520

Odds Ratio = 0.287

Drug Property Information



ATC Code(s):
  • N02CC01 - sumatriptan succinate
    • N02CC - Selective serotonin (5HT1) agonists
    • N02C - ANTIMIGRAINE PREPARATIONS
    • N02 - ANALGESICS
    • N - NERVOUS SYSTEM
Active Ingredient:sumatriptan succinate
Active Ingredient UNII:J8BDZ68989
Drugbank ID:DB00669
PubChem Compound:5358
CTD ID:D018170
PharmGKB:PA451566
CAS Number:103628-46-2
Dosage Form(s):tablet
Route(s) Of Administrator:oral
Daily Dose:
  • 50.0 mg/day N02CC01
Chemical Structure:
SMILE Code:
CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1

Reference

N/A

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The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.

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