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MILRINONE LACTATE


DIR Classification


Classification:Most-DIQT concern
Severity Score:4.0

Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF

  • ADVERSE REACTIONS
  • Cardiovascular Effects
  • Other cardiovascular adverse reactions include hypotension, 2.9% and angina/chest pain, 1.2%.
  • In the post-marketing experience, there have been rare cases of “torsades de pointes” reported.

Postmarketing Surveillance

Contingency Table:

Current Drug
Other Drugs
QT Prolongation
1
24091
Other ADRs
552
38381035

Odds Ratio = 2.887

Drug Property Information



ATC Code(s):
  • C01CE02 - milrinone lactate
    • C01CE - Phosphodiesterase inhibitors
    • C01C - CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    • C01 - CARDIAC THERAPY
    • C - CARDIOVASCULAR SYSTEM
Active Ingredient:MILRINONE LACTATE
Active Ingredient UNII:9K8XR81MO8
Drugbank ID:DB00235
PubChem Compound:4197
CTD ID:D020105
PharmGKB:PA164749171
CAS Number:78415-72-2
Dosage Form(s):injection, solution
Route(s) Of Administrator:intravenous
Daily Dose:
  • 50.0 mg/day C01CE02
Chemical Structure:
SMILE Code:
CC1=C(C=C(C#N)C(=O)N1)C1=CC=NC=C1

Reference

N/A

Disclaimer:

The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.

Any mention of commercial products is for clarification and not intended as endorsement.