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BRENTUXIMAB VEDOTIN
DIR Classification
Classification:Ambiguous
Severity Score:1.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- CLINICAL PHARMACOLOGY
- Pharmacodynamics
- Cardiac Electrophysiology
- At the recommended dose of 1.8 mg/kg, brentuximab vedotin had no large QTc prolongation (>10ms).
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
4
24088
Other ADRs
15507
38366080
Odds Ratio = 0.411
Drug Property Information
ATC Code(s):
- L01XC12 - brentuximab vedotin
- L01XC1 -
- L01XC - Monoclonal antibodies
- L01X - OTHER ANTINEOPLASTIC AGENTS
- L01 - ANTINEOPLASTIC AGENTS
- L - ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Active Ingredient:Brentuximab Vedotin
Active Ingredient UNII:7XL5ISS668
Drugbank ID:DB08870
PubChem Compound:N/ADIR Classification
CTD ID:D000079963
CAS Number:
Dosage Form(s):injection, powder, lyophilized, for solution
Route(s) Of Administrator:intravenous
Daily Dose:
Chemical Structure: 
SMILE Code:
Reference
N/A
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The content of this database of QT prolongation is intended for educational and scientific research purposes only. It is not intended as a substitute for professional medical advice, diagnosis or treatment.
Any mention of commercial products is for clarification and not intended as endorsement.