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GANCICLOVIR
DIR Classification
Classification:Ambiguous
Severity Score:1.0
Description in Drug Labeling: View Full Labeling: SPL in DailyMed | PDF
- ADVERSE REACTIONS
- Postmarketing Experience
- The following adverse reactions have been identified during post-approval use of intravenous ganciclovir. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
- Blood and lymphatic system disorders: hemolytic anemia
- Cardiac disorders: cardiac arrest, cardiac conduction abnormality, torsades de pointes, ventricular tachycardia
Postmarketing Surveillance
Contingency Table:
Current Drug
Other Drugs
QT Prolongation
1
24091
Other ADRs
4404
38377183
Odds Ratio = 0.362
Drug Property Information
ATC Code(s):
- J05AB06 - ganciclovir
- J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors
- J05A - DIRECT ACTING ANTIVIRALS
- J05 - ANTIVIRALS FOR SYSTEMIC USE
- J - ANTIINFECTIVES FOR SYSTEMIC USE
- S01AD09 - ganciclovir
- S01AD - Antivirals
- S01A - ANTIINFECTIVES
- S01 - OPHTHALMOLOGICALS
- S - SENSORY ORGANS
Active Ingredient:GANCICLOVIR
Active Ingredient UNII:P9G3CKZ4P5
Drugbank ID:DB01004
PubChem Compound:3454
CTD ID:D015774
PharmGKB:PA449733
CAS Number:82410-32-0
Dosage Form(s):injection, solution
Route(s) Of Administrator:intravenous
Daily Dose:
- 3000.0 mg/day J05AB06
Chemical Structure: 
SMILE Code:
NC1=NC2=C(N=CN2COC(CO)CO)C(=O)N1
NC1=NC2=C(N=CN2COC(CO)CO)C(=O)N1
Reference
1: The Contribution of National Spontaneous Reporting Systems to Detect Signals of Torsadogenicity: Issues Emerging from the ARITMO Project.
[Raschi Emanuel,Poluzzi Elisabetta,Salvo Francesco,Koci Ariola,Suling Marc,Antoniazzi Stefania,Perina Luisella,Hazell Lorna,Moretti Ugo,Sturkenboom Miriam,Garbe Edeltraut,Pariente Antoine,De Ponti Fabrizio]Drug Saf,2016 Jan;39(1):59-68. PMID: 26446144
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